CBD oil for sleep: what trials show, and CBN vs CBD

26/09/2026
Formula Swiss CBN oil 5% with 0% THC in an amber dropper bottle

Does CBD oil help you sleep? Several trials found better self-rated sleep quality or well-being with CBD, and in a 1,793-person study 15 mg CBD improved sleep about as much as 5 mg melatonin. Results are not yet consistent: a small trial in people with insomnia found no difference from placebo. Unlike a sleeping pill, CBD did not disrupt normal sleep in a sleep laboratory.

This guide sums up what the clinical trials tested and found, how CBN compares with CBD and melatonin, which doses and timing studies used, and what to know about next-day alertness. We make CBD and CBN oils in Switzerland. None of our products are medicines, and nothing here is advice on treating a sleep disorder.

Key facts

CBD-only trials
Mixed; better self-rated sleep quality in several trials, no significant pooled effect in a 2025 meta-analysis.
Cannabinoids overall
Some benefit on sleep time and quality in recent reviews; the certainty of the evidence is still low.
CBN
Fewer night-time awakenings at 20 mg in the largest trial; faster sleep onset at 300 mg in another; larger trials needed.
Doses tested
15–450 mg CBD a day, taken by mouth in research settings.
Timing in trials
Usually 30–60 minutes before bed.
Our CBN oil
5% CBN, THC-free, for use on the skin

Does CBD oil help you sleep?

The evidence is still developing, and it points three ways.

  • Some positive signals. In small and medium-sized trials, people taking CBD reported better sleep quality or well-being. In one trial, measured sleep efficiency was also better after two weeks.
  • Some trials without an effect. In a randomised trial of CBD alone in people with moderate to severe insomnia, insomnia severity, time to fall asleep and time awake at night did not differ from placebo.
  • Prescription cannabis medicines. The largest improvements in insomnia came from prescription products containing THC, which are not sold as consumer oils. In a 2025 meta-analysis of six trials, CBD-only products did not reach statistical significance on sleep quality.

Unlike a sleeping pill, CBD did not alter the normal sleep cycle of healthy volunteers, even at a single 300 mg dose.

What do clinical trials on CBD and sleep show?

These are the randomised trials most often cited on CBD, CBN and sleep. Who took part, what they took and whether the main outcome changed matter more than the headline.

Randomised trials of cannabinoids and sleep
Study Who and what Main finding
Linares 2018 27 healthy adults; CBD 300 mg, single dose No effect on the sleep–wake cycle compared with placebo
Walsh 2021 24 adults with chronic insomnia; THC-dominant extract (THC 20 mg/ml, CBN 2 mg/ml, CBD 1 mg/ml), 2 weeks Less insomnia severity, longer total sleep
Ried 2023 29 adults with insomnia; oil with THC 10 mg/ml + CBD 15 mg/ml, 2 weeks Improved sleep; the authors note loss of blinding
Kisiolek 2023 28 healthy young adults; CBD 50 mg daily, 8 weeks Better self-reported sleep quality; no change in sleep quantity
Saleska 2024 1,793 adults with sleep disturbance; CBD 15 mg capsules, with or without CBN, CBC or melatonin 5 mg, 4 weeks All groups improved (no placebo group); CBN or CBC added no benefit; CBD did not beat melatonin
Bonn-Miller 2024 293 adults with poor sleep; CBN 20 mg, with or without CBD (10–100 mg), 7 nights Main outcome not significant; fewer awakenings with CBN 20 mg; adding CBD did not help
Narayan 2024 30 adults with moderate–severe insomnia; CBD 150 mg nightly, 2 weeks No difference on insomnia severity or main sleep measures; better well-being
Dujic 2025 64 adults with high blood pressure; CBD 225–450 mg daily, 5 weeks Less daytime sleepiness; no change in sleep quality
Lavender 2026 20 adults with insomnia disorder; CBN 30 mg or 300 mg, single nights Main outcome not significant; 300 mg shortened time to fall asleep

Two reviews put the trials together:

  • A 2025 meta-analysis in Sleep Medicine Reviews (da Silva 2025) of six trials (1,077 people) found that cannabinoids improved self-reported sleep quality overall; CBD-only products did not reach statistical significance on their own.
  • A 2026 review in The Lancet Psychiatry (Wilson 2026) found that cannabinoids increased sleep time in people with insomnia. The certainty of the evidence was generally low. Side effects were more common than with placebo, but serious ones were not.

What is CBN, and is it better than CBD for sleep?

CBN (cannabinol) is a minor cannabinoid. It forms when THC in the cannabis plant breaks down with exposure to air, light and heat, which is why aged cannabis contains more of it. Read more in What is CBN (cannabinol)?

THC slowly turns into CBN when exposed to air, light and heat THC air · light · heat over time CBN

CBN has a reputation as the "sleepy" cannabinoid, but the human evidence is still thin:

  • In the largest CBN trial (Bonn-Miller 2024) (293 adults with poor sleep, 7 nights), 20 mg CBN did not significantly improve the main outcome, sleep quality. It did reduce night-time awakenings and overall sleep disturbance. Adding CBD did not improve results.
  • In a 2026 laboratory trial (Lavender 2026) in 20 adults with insomnia disorder, neither 30 mg nor 300 mg CBN reduced time awake after falling asleep, the main outcome. The 300 mg dose shortened the time to fall asleep and improved rated sleep quality. The authors advise caution about next-day impairment at high doses.
  • In the 1,793-person comparison trial (Saleska 2024), all groups improved, including CBD with CBN; adding CBN to CBD brought no extra benefit (no placebo group).

Bottom line: CBN's signal for fewer night-time awakenings is promising, but it hasn't yet been shown to beat CBD. Larger trials are needed.

Does CBN get you high?

CBN comes from THC, but it is much weaker. A 2021 review (Corroon 2021) found that most human studies showed no cannabis-like effects from CBN on its own.

What is in our CBN oil?

From the label of our CBN Oil in MCT (5% CBN):

  • 10 ml bottle with 500 mg CBN (5%) in MCT oil; about 250 drops, which is 2 mg CBN per drop
  • Label directions: two to three drops applied directly to the skin, 2–3 times a day; labelled for topical use only
  • Hemp extract from Swiss hemp grown following organic principles, made by supercritical CO2 extraction; THC-free, and the label states it has no intoxicating effect
  • Made in Switzerland under Good Manufacturing Practice (GMP) and ISO 22716; notified as a cosmetic in the EU (CPNP) and the UK (SCPN)

The certificate for each CBN oil batch is on our test results page.

CBD vs CBN vs melatonin: how do they differ?

CBD, CBN and melatonin compared
What it is Sleep evidence
CBD Main non-intoxicating cannabinoid in hemp Mixed; better self-rated sleep in several trials, and similar to melatonin in the one large head-to-head trial
CBN Minor cannabinoid formed as THC ages Early; fewer awakenings in one trial, main outcomes not met
Melatonin Hormone that helps regulate the sleep–wake cycle Modest: about 7 minutes faster to fall asleep and 8 minutes more sleep in a meta-analysis of 19 trials (Ferracioli-Oda 2013)

In the one large head-to-head trial, 15 mg CBD improved sleep about as much as 5 mg melatonin, and adding melatonin or CBN to CBD brought no extra benefit (Saleska 2024; no placebo group).

How much CBD do people take for sleep, and when?

There is no established CBD dose for sleep. This is what the studies used:

Bottle of Lucerne Calm CBD oil with Formula Swiss branding
Lucerne Calm: THC-free, with 20% CBD, 3% CBG and 0.5% CBDA. Follow the directions on the label.
  • Amounts (study data; taken by mouth in the trials): 15–450 mg CBD a day, and 20–300 mg CBN. Low-dose trials (15–50 mg) reported better self-rated sleep quality, but the 15 mg trial had no placebo group. The 150 mg insomnia trial did not beat placebo on its main outcome, so a higher dose does not simply mean a better effect.
  • Timing: most trials gave the dose 30–60 minutes before bed, for example 60 minutes in the 150 mg trial (Narayan 2024).
  • Duration: from a single night to eight weeks. Effects of longer use are largely unknown.

About our oils

Our CBD and CBN oils, including Lucerne Calm (a THC-free oil with 20% CBD, 3% CBG and 0.5% CBDA per 30 ml bottle), are notified as cosmetics for use on the skin, and their labels give directions for topical use only. So we don't give oral dosing advice for them. Read the label of the product you use, and talk to your doctor or pharmacist if you take other medicines. For drops and mg per strength, see our CBD oil dosage guide.

A calm evening routine

A steady routine is the foundation of good sleep. The NHS insomnia advice suggests:

  1. Get up at the same time every day, including weekends.
  2. Avoid caffeine, alcohol and smoking for at least 6 hours before bed, and don't eat large meals late at night.
  3. Don't exercise for at least 4 hours before bed; exercise during the day instead.
  4. Relax for at least an hour before bed, for example with a bath or a book, and put screens away.
  5. Keep the bedroom dark and quiet, and only go to bed when you feel sleepy.

Does CBD make you sleepy the next day?

Studies so far suggest CBD on its own has little next-day effect:

  • In the 150 mg insomnia trial, daytime thinking and memory scores were unchanged (Narayan 2025) after two weeks. Participants did report more dry mouth.
  • In a driving-simulator trial (McCartney 2022), single oral doses of 15, 300 and 1,500 mg CBD did not make people feel intoxicated and are unlikely to impair driving, although some comparisons were inconclusive.
  • CBN is different at high doses. In the 2026 insomnia trial, 300 mg CBN changed some next-day driving and reaction-time measures, and the authors advise caution.

For drivers, THC is the real issue: full-spectrum products can contain traces of it, and the rules differ by country (see CBD, drug tests and driving). Never drive when you feel sleepy, whatever the cause.

Why are sleep researchers interested in cannabinoids?

Poor sleep is common and costly. In a nationally representative Dutch survey (Kerkhof 2017) of 2,089 adults aged 18–70 (data collected in 2012, published in 2016), 32.1% had a general sleep disturbance. A RAND Europe study (Hafner et al. 2016) estimated that too little sleep costs up to 1.56% of GDP a year in Germany and 1.86% in the United Kingdom.

Researchers linked to the University of Groningen are planning a large double-blind, randomised, placebo-controlled crossover study of full-spectrum CBD and CBN products with more than 300 participants in the Netherlands. Formula Swiss is involved in this study. It will include patients with irritable bowel syndrome (IBS) and patients with musculoskeletal pain from rheumatoid arthritis, and ask whether cannabinoids improve their sleep, symptoms and quality of life. The study is still being planned, so there are no results yet. We will add them here when they are available.

When should you get help for poor sleep?

If poor sleep has lasted for months, take it seriously. The European Insomnia Guideline (Riemann 2023) recommends cognitive behavioural therapy for insomnia (CBT-I), in person or online, as the first treatment for chronic insomnia in adults. Medication is considered when CBT-I doesn't help enough. CBD and CBN are not part of these recommendations. See your doctor if you snore loudly, stop breathing during sleep, feel very sleepy during the day, or if poor sleep affects your mood or work.

Safety: who should be careful

  • Medicines, including sleeping pills: CBD can interact with other medicines, and EFSA notes a liver concern, particularly when CBD is combined with medication. Talk to your doctor or pharmacist first, and see CBD and medication.
  • Pregnancy and breastfeeding: not recommended.
  • Under 25s: EFSA says safety has not been established.
  • Side effects in trials: usually mild, for example dry mouth. They were more common with cannabinoids than with placebo, but serious ones were not. See CBD side effects.
  • Driving: avoid products that contain THC before driving.

Frequently asked questions

Is CBD oil good for sleep?

Several trials found better self-reported sleep quality or well-being with CBD, and one large study found it comparable to melatonin. The evidence isn't consistent yet: a small insomnia trial and a 2025 meta-analysis found no significant effect for CBD alone.

How long before bed should you take CBD?

Most sleep trials gave CBD 30–60 minutes before bed. There is no official recommendation. Always follow the label of the product you use; our oils are labelled for topical use.

Is CBN better than CBD for sleep?

Not yet shown. In the largest CBN trial, 20 mg CBN reduced night-time awakenings, although the main sleep-quality score did not change significantly. In a 2026 trial, 300 mg CBN shortened the time to fall asleep. Larger trials are needed to compare it directly with CBD.

Is CBD better than melatonin?

In the one large head-to-head trial, 15 mg CBD and 5 mg melatonin improved sleep by similar amounts. Melatonin has more trials behind it, but its average effect is modest: about 7 minutes faster to fall asleep.

Does CBD make you sleepy?

Usually not in the way a sleeping pill does. A single 300 mg dose did not change the sleep cycle of healthy volunteers, and 150 mg nightly did not affect next-day cognition.

Does CBN oil get you high?

CBN is much weaker than THC, and most human studies found no cannabis-like effects from CBN on its own. Our CBN oil is THC-free, and its label states that it has no intoxicating effect.

Can CBD keep you awake?

In the trials cited here, CBD was not linked to sleeplessness. In a five-week trial in people with high blood pressure, CBD reduced daytime sleepiness without changing sleep quality (Dujic 2025), and a single 300 mg dose did not alter the normal sleep cycle of healthy volunteers (Linares 2018).

Is CBD habit-forming like sleeping pills?

There are no signs of that. The World Health Organization's expert committee concluded in 2018 that in humans CBD "exhibits no effects indicative of any abuse or dependence potential", and CBD did not alter the normal sleep cycle of healthy volunteers (Linares 2018).

Can I take CBD with sleeping pills or other medicines?

Talk to your doctor or pharmacist first. CBD can interact with medicines, and EFSA says its safety for people taking medication has not been established.

This article is for general information only and is not medical advice. Our products are not medicines and are not intended to diagnose, treat, cure or prevent any disease. See our disclaimer.

Last reviewed:

Sources

  1. Linares IMP et al. No acute effects of cannabidiol on the sleep-wake cycle of healthy subjects. Front Pharmacol 2018. PMID 29674967
  2. Walsh JH et al. Treating insomnia symptoms with medicinal cannabis: a randomized, crossover trial. Sleep 2021. PMID 34115851
  3. Ried K et al. Medicinal cannabis improves sleep in adults with insomnia: a randomised crossover study. J Sleep Res 2023. PMID 36539991
  4. Kisiolek JN et al. Eight weeks of daily cannabidiol supplementation improves sleep quality and immune cell cytotoxicity. Nutrients 2023. PMID 37836465
  5. Saleska JL et al. The safety and comparative effectiveness of non-psychoactive cannabinoid formulations for the improvement of sleep. J Am Nutr Assoc 2024. PMID 37162192
  6. Bonn-Miller MO et al. A double-blind, randomized, placebo-controlled study of the safety and effects of CBN with and without CBD on sleep quality. Exp Clin Psychopharmacol 2024. PMID 37796540
  7. Narayan AJ et al. Cannabidiol for moderate–severe insomnia: a randomized controlled pilot trial of 150 mg of nightly dosing. J Clin Sleep Med 2024. PMID 38174873
  8. Narayan AJ et al. The effect of nightly use of 150 mg cannabidiol on daytime neurocognitive performance in primary insomnia. Psychopharmacology 2025. PMID 39153080
  9. Dujic G et al. Chronic cannabidiol administration mitigates excessive daytime sleepiness and fatigue in patients with primary hypertension. Cannabis Cannabinoid Res 2025. PMID 39187263
  10. Lavender IG et al. Cannabinol for acute treatment of insomnia disorder in a randomized placebo-controlled crossover trial. J Sleep Res 2026. PMC13357646
  11. da Silva GHS et al. Effectiveness of cannabinoids on subjective sleep quality: a systematic review and meta-analysis. Sleep Med Rev 2025. PMID 40929927
  12. Wilson J et al. The efficacy and safety of cannabinoids for the treatment of mental disorders and substance use disorders. Lancet Psychiatry 2026. PMID 41856154
  13. Ferracioli-Oda E et al. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One 2013. PMID 23691095
  14. McCartney D et al. Effects of cannabidiol on simulated driving and cognitive performance. J Psychopharmacol 2022. PMID 35637624
  15. Kerkhof GA. Epidemiology of sleep and sleep disorders in The Netherlands. Sleep Med 2017 (online 2016). PMID 28215254
  16. RAND Europe. The value of the sleep economy (Hafner M et al., Why sleep matters, 2016)
  17. Corroon J. Cannabinol and sleep: separating fact from fiction. Cannabis Cannabinoid Res 2021. PMID 34468204
  18. Riemann D et al. The European Insomnia Guideline: an update on the diagnosis and treatment of insomnia 2023. J Sleep Res 2023. PMID 38016484
  19. EFSA NDA Panel. Update of the statement on safety of cannabidiol as a novel food. EFSA Journal 2026. doi:10.2903/j.efsa.2026.9862
  20. World Health Organization, Expert Committee on Drug Dependence. Cannabidiol (CBD): critical review report. 40th meeting, Geneva, June 2018
  21. NHS. Insomnia
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Robin Roy Krigslund-Hansen

Robin Roy Krigslund-Hansen

За автора

Robin Roy Krigslund-Hansen е основател и главен изпълнителен директор на Formula Swiss и отговаря за формулирането на продуктите. От основаването на компанията през 2013 г. пише за конопа, CBD и канабис индустрията. Гледната му точка се основава на изграждането на Formula Swiss, разговорите с изследователи и подкрепата за изследванията на CBD.

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